How much caffeine is in NoDoz?

One tablet of NoDoz contains 200 mg of caffeine.

That's about 2 cups of brewed coffee, and half of the 400 mg a day the FDA cites for most healthy adults.

Source: DailyMed (U.S. National Library of Medicine) · checked 10 Nov 2026

When did you take it?

Taken at 3 pm, about 69 mg is still in you at an 11 pm bedtime. That might affect your sleep.

Bedtime

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Latest time to take it

For an 11 pm bedtime, one tablet of NoDoz taken by about 12:35 pm keeps most people under 50 mg of caffeine through the night. The table works it out for other bedtimes and for how sensitive you are: it is the latest time to take one so that the caffeine left stays under the line all night.

Bedtime	Very sensitive under 25 mg	Average under 50 mg	Not very sensitive under 100 mg
9 pm	5:35 am	10:35 am	3:35 pm
10 pm	6:35 am	11:35 am	4:35 pm
11 pm	7:35 am	12:35 pm	5:35 pm
Midnight	8:35 am	1:35 pm	6:35 pm
1 am	9:35 am	2:35 pm	7:35 pm

One unit as listed on the label, average clearance (half-life 5 h), 8 hours of sleep. "Any time" means even one at bedtime stays under the line. Follow the label or ask your pharmacist about how much and how often to take it; this table is only about sleep.

How long it lasts

The caffeine from one tablet of NoDoz peaks in your blood about 70 minutes after you take it, at roughly 171 mg. Half of it is gone in about 5 hours for an average adult; that ranges from roughly 3 to 7 hours, and longer in pregnancy or with some medicines.

Time after	3 hours	6 hours	9 hours	12 hours
Still in you	139 mg	92 mg	60 mg	40 mg

So one taken at 3 pm leaves about 69 mg at 11 pm. How long caffeine lasts explains the curve.

How it compares

NoDoz is stronger than 61% of the 34 supplements and medicines we track, by caffeine per serving.

To reach 400 mg in a day you would need about 2 of these.

Less caffeine

Mr. Hyde Pre-Workout 190 mg, 1 scoop, Infinite
Gold Standard Pre-Workout 175 mg, 1 scoop
C4 Ripped 150 mg, 1 scoop

More caffeine

Pre-Kaged 274 mg, 1 scoop
Gold Standard Pre-Advanced 300 mg, 1 scoop
Pre-Kaged Elite 388 mg, 1 scoop

Same caffeine: 1st Phorm Project-1 Pre-Workout, C4 Original Pre-Workout, Caffeine Pills (200 mg).

FAQ

Is NoDoz high in caffeine?

Yes, very. One tablet of NoDoz contains 200 mg, which is 2.1 times an 8 fl oz cup of brewed coffee (95 mg).

Can I take NoDoz at night?

Not if you want to sleep well. Taken at 7 pm, it leaves about 121 mg in an average adult at an 11 pm bedtime, above the 50 mg most people sleep fine with. The latest time for an 11 pm bedtime is about 12:35 pm.

How long does the caffeine in NoDoz last?

It peaks about 70 minutes after you take it. Of the 200 mg, about 92 mg is still in you 6 hours later and 40 mg after 12 hours, for an average adult with a 5-hour half-life.

Does NoDoz have more caffeine than a cup of coffee?

Yes. One tablet of NoDoz contains 200 mg; an 8 fl oz cup of coffee has 95 mg.

Method and limits

The caffeine figure comes from DailyMed (U.S. National Library of Medicine); it is the amount the label lists per unit. The curves use a standard one-compartment model with an average 5-hour half-life and a sleep-friendly line of 50 mg; your own body may clear caffeine faster or slower. How it works has the details.

These are estimates for information, not medical advice. If you are pregnant, ask your doctor; common guidance is under 200 mg a day. This is a medicine: follow the label and ask your pharmacist or doctor about dosing.